General Information

  • ID:  hor000314
  • Uniprot ID:  NA
  • Protein name:  Callatostatin 4
  • Gene name:  NA
  • Organism:  Calliphora vomitoria
  • Family:  Allatostatin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  XRPYSFGL
  • Length:  8
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Inhibit juvenile hormone production
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000314_AF2.pdbhor000314_ESM.pdb

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Physical Information

Mass: 105597 Formula: C40H56N10O9
Absent amino acids: ACDEHIKMNQTVW Common amino acids: FGLPRSYX
pI: 9.35 Basic residues: 1
Polar residues: 3 Hydrophobic residues: 2
Hydrophobicity: -25 Boman Index: -962
Half-Life: Half-Life Yeast:
Half-Life E.Coli: Aliphatic Index 48.75
Instability Index: 3157.5 Extinction Coefficient cystines: 1490
Absorbance 280nm: 212.86

Literature

  • PubMed ID:  8460157
  • Title:  Callatostatins: Neuropeptides From the Blowfly Calliphora Vomitoria With Sequence Homology to Cockroach Allatostatins